PerfTool: A software platform for investigating bolus-tracking perfusion imaging quantification strategies
نویسندگان
چکیده
منابع مشابه
Quantification Issues in Bolus-Tracking Perfusion MRI
Bolus-tracking perfusion MRI is based on the monitoring of the first passage of a bolus of contrast agent through the brain tissue and a brain-feeding artery. The contrast agent is injected rapidly in the antecubital vein in the patients arm by means of an MR-compatible power injector. This bolus of contrast agent is pushed in the direction of the heart by means of a saline flush. Continuous dy...
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Cerebral perfusion may be visualized by the dynamic imaging of an intravenously injected bolus (a few milliliters) of clinically approved gadolinium-containing contrast media. During its passage through the vasculature of the brain, the contrast agent induces magnetic field disturbances, which can be seen as signal loss on appropriately weighted dynamic MRI. This article deals with the quantita...
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The principles of cerebral perfusion imaging by the method of dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) (bolus tracking) are described. The MRI signals underlying DSC-MRI are discussed. Tracer kinetics procedures are defined to calculate images of cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT). Two general categories of numerical p...
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BACKGROUND MR techniques have been very powerful in providing indicators of tissue perfusion, particularly in studies of cerebral ischemia. There is considerable interest in performing absolute perfusion measurements, with the aim of improving the characterization of tissue "at risk" of stroke. However, some important caveats relating to absolute measurements need to be taken into account. The ...
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Different software tools for quantification of myocardial perfusion SPECT (MPS) studies are routinely used. Several perfusion parameters can be computed automatically. Interpretation of the MPS should start with visual inspection of the rotating planar images, visual analysis of reconstructed SPECT slices and then quantitative analysis to confirm the visual impression. Quantification should be...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2007
ISSN: 1053-1807,1522-2586
DOI: 10.1002/jmri.20843